Rowan-Classes/8th-Semester-Spring-2025/frontiers/notes/technical-overview.md
2025-03-10 15:24:54 -04:00

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Macromolecule storage techniques

  • Several KBs have been stored successfully in DNA chains
  • Synthetic molecules also work
  • Technology is mostly limited by slow reading and writing speeds
  • Sequencing methods include tandem mass spectrometry (MS/MS), enzyme-based approaches, and nanopore threading.
  • Using synthetic polymers allows the molecular structure to be tuned to facilitate sequencing using "routine analytical instruments".

Synthesis of coded macromolecules

  • Solid-phase iterative chemistry